The Cholesterol Conspiracy Podcast by Ladd McNamara, M.D. » Vitamins http://www.cholesterolconspiracy.com Ladd McNamara M.D. Reveals the Truth About Statins and Cholestorol Thu, 18 Feb 2010 18:04:52 +0000 http://wordpress.org/?v=2.8.5 en hourly 1 Ladd McNamara M.D. Reveals the Truth About Statins and Cholestorol The Cholesterol Conspiracy Podcast by Ladd McNamara, M.D. no 2008 - Total Wellness Network Ladd McNamara M.D. Reveals the Truth About Statins and Cholestorol The Cholesterol Conspiracy Podcast by Ladd McNamara, M.D. » Vitamins http://www.cholesterolconspiracy.net/graphics/album_144-144_v01.jpg http://www.cholesterolconspiracy.com Episode 16: The “Best” Way to Reduce the Risk of Cardiac Death: Part 3 (According to Dr. Ladd McNamara) http://www.cholesterolconspiracy.com/episode-16-the-real-and-alternative-way-to-reduce-the-risk-of-death-from-heart-disease-and-stroke-part-3/ http://www.cholesterolconspiracy.com/episode-16-the-real-and-alternative-way-to-reduce-the-risk-of-death-from-heart-disease-and-stroke-part-3/#comments Tue, 01 Dec 2009 04:19:49 +0000 laddmcnamara http://www.cholesterolconspiracy.com/?p=78 In this episode Dr. Ladd McNamara discusses vitamins, minerals, antioxidants, and essential fatty acids: a real an alternative way to reduce the risk of death from heart disease and stroke.

  • Chapter 33: Vitamins, Minerals, Antioxidants, and Essential Fatty Acids: The Real Way to Reduce the Risk of Death from Heart Disease and Stroke – Part 3

Chapter Excerpts

Alpha-Lipoic Acid works in many ways to protect against disease and maintain health. ALA protects LDL cholesterol from oxidation, reduces the inflammatory reaction of the arteries, along with magnesium helps to maintain a health blood pressure. Alpha-Lipoic Acid works together with co-enzyme Q10 in the metabolism of sugar into energy.

Olive Oil and Olive Oil Extracts contain polyphenol antioxidants that are in part responsible for the benefits of the Mediterranean diet. Studies have shown those who consume more of these antioxidant compounds have a greatly reduced risk of heart disease and cancer, let alone a prolongation of life.

Fish oil supplements (containing DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid) have been shown to decrease the risk of cardiac death greater than the use of statin drugs, …and without any toxic side-effects. Thus, more evidence of the Cholesterol Conspiracy.

In addition to magnesium supplementation, researchers are finding promise in the higher rates of survival after heart attacks when high-dose antioxidants are commenced shortly after such an attack.

Diets high in both soluble and insoluble fiber help reduce blood lipid levels, cholesterol, and insulin intolerance.

Ladd McNamara, M.D.

Chapter References

  • 130: Zhang WJ, Frei B. Alpha-lipoic acid inhibits TNF-alpha-induced NFkappa B activation and adhesion molecule expression in human aortic endothelial cells. FASEB J 2001 Nov;15(13):2423-2432.
  • 131: El Midaoui A, de Champlain J. Prevention of hypertension, insulin resistance, and oxidative stress by alpha-lipoic acid. Hypertension 2002 Feb;39(2):303-307.
  • 132: Takaoka M, et al. Effects of alpha-lipoic acid on deoxycorticos-terone acetate-salt-induced hypertension in rats. Eur J Pharmacol 2001 Jul;20;424(2):121-129.
  • 133: Koufaki M, et al. Novel potent inhibitors of lipid peroxidation with protective effects against reperfusion arrhythmias. J Med Chem 2001 Nov 22;44(24):4300-4303.
  • 134: Gonzalez-Perez O, Gonzalez-Castaneda R, Huerta M, et al. Beneficial effects of -lipoic acid plus vitamin E on neurological deficit, reactive gliosis and neuronal remodeling in the penumbra of the ischemic rat brain. Neuroscience Letters, 2002 March 15, 321(5);1:100-104.
  • 135: Chen C et al. Endogenous sex hormones and prostate cancer risk: a case-control study nested within the carotene and retinal efficacy trial. Cancer Epidimeiol Biomarkers Prev. 2003 Dec;12(12):1410-1416.
  • 136: Upritchard J, Suterhland W, Mann J. Effect of supplementation with tomato juice, vitamin E, and vitamin C oxidation and products of inflammatory activity in type 2 diabetes. Diabetes Care. 2000 Jun;23(6):733-738.
  • 137: Decker E, et al. Inhibition of low-density lipoprotein oxidation by carnosine histidine. J Agric Food Chem 2001 Jan;49(1):511-516.
  • 138: Owen RW, et al. Olive oil consumption and health: the possible role of antioxidants. Lancet Oncol, 2000, Oct., 1:107-12.
  • 139: Visioli F, et al. Antioxidant and other biological activities of phenols from olives and olive oil. Med Res Rev. 2002 Jan;22(1):65-75.
  • 140: Simopoulos Ap. The traditional diet of Greece and cancer. Eur J Cancer Prev. 2004 Jun;13(3):219-30.
  • 141: Visioli F., et al. Low density lipoprotein oxidation is inhibited in vitro by olive oil constituents. Atherosclerosis. 1995 Sep;117(1):25-32.
  • 142: Cullinen K. Olive oil in the treatment of hypercholesterolemia. Med Health R.I. 2006 Mar;89(3):113.
  • 143: Nagyova A, et al. Effects of dietary extra virgin olive oil on serum lipid resistance to oxidation and fatty acid composition in elderly lipidemic patients. Bratisl Lek Listy. 2003;104(7-8):218-21.
  • 144: Martinez-Gonzalez MA. The SUN cohort study (Seguimiento University of Navarra). Public Health Nutr. 2006 Feb;9(1A):127-31.
  • 145: Bogani P., et al. Postprandial anti-inflammatory and antioxidant effects of extra virgin olive oil. Atherosclerosis. 2006 Feb 17; [Epub ahead of print].
  • 146: Fito M., et al. Antioxidant effect of virgin olive oil in patients with stable coronary heart disease: a randomized, crossover, controlled, clinical trial. Atherosclerosis. 2005 Jul;181(1):149-58.
  • 147: Fernandez-Jarne E., et al. Risk of first non-fatal myocardial infarction negatively associated with olive oil consumption: a case-control study in Spain. Int J Epidemiol. 2002, Apr;31(2):474-80.
  • 148: Visioli F., Galli C. Antiatherogenic components of olive oil. Curr Atheroscler Rep. 2001. Jan;3(1):64-7.
  • 149: Visioli F., et al. Low density lipoprotein oxidation is inhibited in vitro by olive oil constituents. Atherosclerosis. 1995 Sep;117(1):25-32.
  • 150: Nestel P, et al. The n-3 fatty acids eiosapentaenoid acid and docosahexaenoic acid increase systemic arterial compliance in humans. Am J Clin Nutr 2002 Aug;76(2):326-330.
  • 151: McLennan O. Myocardial membrane fatty acids and the antiarrhythmic actions of dietary fish oil in animal models. Lipids 2001 36 Suppl: S111-S114.
  • 152: Marchioli R, Barzi F, Bomba E, et al. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italian per lo Studio dells Soprvvivenza nell’Infarto Micardico (GISSI)-Prevenzione. Circulation. 2002 Apr 23;105:1897-1903.
  • 56: Rosenson RS. Statins in atherosclerosis: lipid-lowering agents with antioxidant capabilities. Atherosclerosis. 2004. Mar;173(1):1-12.
  • 57: Tsimikas S, et al. High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial. Circulation. 2004 Sep 14;110(11):1406-12.
  • 152: Marchioli R, Barzi F, Bomba E, et al. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italian per lo Studio dells Soprvvivenza nell’Infarto Micardico (GISSI)-Prevenzione. Circulation. 2002 Apr 23;105:1897-1903.
  • 154: Bernier M, et al. Reperfusion-induced arrhythmias and oxygen-derived free radicals. Circulation Res. 1986 58:331-340.
  • 203: Studer M, et al. Effect of different antilipidemic agents and diets on mortality: a systematic review. Archives of Internal Medicine, 2005 Apr 11;165(7):725-30.
  • 153: Grech E, et. al. Reperfusion injury after acute myocardial infarction. Brit Med J 1995 310:477-478.
  • 154: Bernier M, et al. Reperfusion-induced arrhythmias and oxygen-derived free radicals. Circulation Res. 1986 58:331-340.
  • 155: Chamiec T, et al. Effects of antioxidant vitamins C and E on signalaveraged electrocardiogram in acute myocardial infarction. Am J Cardiol. 1996 77:277-281.
  • 156: Dzizinskii AA, et al. Effects of antioxidants and membrane protectors on clinical course and hemodynamics of patients of myocardial infarct. Ross Med Zh. 1992 1:32-34.
  • 157: Kramer J, et al. Magnesium-deficiency potentiates free radical production associated with post-ischemic injury to rat hearts: vitamin E affords protection. Free Rad Bio Med. 1994 16:6:713-723.
  • 158: Altura BM. Cardiovascular risk factors and magnesium: relationships to atherosclerosis, ischemic heart disease and hypertension. magnesium and trace elements. Switzerland, S. Karger AG, Basel, 1991-92;10:182-192.
  • 159: Van Leer EM, et al. Dietary calcium, potassium, magnesium and blood pressure in the Netherlands. Internation J Epidem. 1995 24:6:1117-23.
  • 160: Bernier M, et al. Reperfusion-induced arrhythmias and oxygen-derived free radicals. Circulation Res. 1986 58:331-340.
  • 161: Chamiec T, et al. Effects of antioxidant vitamins C and E on signalaveraged electrocardiogram in acute myocardial infarction. Am J Cardiol. 1996 77:277-281.
  • 162: Dzizinskii AA, et al. Effects of antioxidants and membrane protectors on clinical course and hemodynamics of patients of myocardial infarct. Ross Med Zh. 1992 1:32-34.

Ladd McNamara, M.D.

]]> http://www.cholesterolconspiracy.com/episode-16-the-real-and-alternative-way-to-reduce-the-risk-of-death-from-heart-disease-and-stroke-part-3/feed/ 0 Antioxidants,Cholesterol Conspiracy,Essential Fatty Acids,Heart Disease,Ladd McNamara,Minerals,Stroke,Vitamins In this episode Dr. Ladd McNamara discusses vitamins, minerals, antioxidants, and essential fatty acids: a real an alternative way to reduce the risk of death from heart disease and stroke. - Chapter 33: Vitamins, Minerals, Antioxidants, In this episode Dr. Ladd McNamara discusses vitamins, minerals, antioxidants, and essential fatty acids: a real an alternative way to reduce the risk of death from heart disease and stroke. Chapter 33: Vitamins, Minerals, Antioxidants, and Essential Fatty Acids: The Real Way to Reduce the Risk of Death from Heart Disease and Stroke - Part 3 Chapter Excerpts Alpha-Lipoic Acid works in many ways to protect against disease and maintain health. ALA protects LDL cholesterol from oxidation, reduces the inflammatory reaction of the arteries, along with magnesium helps to maintain a health blood pressure. Alpha-Lipoic Acid works together with co-enzyme Q10 in the metabolism of sugar into energy. Olive Oil and Olive Oil Extracts contain polyphenol antioxidants that are in part responsible for the benefits of the Mediterranean diet. Studies have shown those who consume more of these antioxidant compounds have a greatly reduced risk of heart disease and cancer, let alone a prolongation of life. Fish oil supplements (containing DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid) have been shown to decrease the risk of cardiac death greater than the use of statin drugs, ...and without any toxic side-effects. Thus, more evidence of the Cholesterol Conspiracy. In addition to magnesium supplementation, researchers are finding promise in the higher rates of survival after heart attacks when high-dose antioxidants are commenced shortly after such an attack. Diets high in both soluble and insoluble fiber help reduce blood lipid levels, cholesterol, and insulin intolerance. Ladd McNamara, M.D. Chapter References 130: Zhang WJ, Frei B. Alpha-lipoic acid inhibits TNF-alpha-induced NFkappa B activation and adhesion molecule expression in human aortic endothelial cells. FASEB J 2001 Nov;15(13):2423-2432. 131: El Midaoui A, de Champlain J. Prevention of hypertension, insulin resistance, and oxidative stress by alpha-lipoic acid. Hypertension 2002 Feb;39(2):303-307. 132: Takaoka M, et al. Effects of alpha-lipoic acid on deoxycorticos-terone acetate-salt-induced hypertension in rats. Eur J Pharmacol 2001 Jul;20;424(2):121-129. 133: Koufaki M, et al. Novel potent inhibitors of lipid peroxidation with protective effects against reperfusion arrhythmias. J Med Chem 2001 Nov 22;44(24):4300-4303. 134: Gonzalez-Perez O, Gonzalez-Castaneda R, Huerta M, et al. Beneficial effects of -lipoic acid plus vitamin E on neurological deficit, reactive gliosis and neuronal remodeling in the penumbra of the ischemic rat brain. Neuroscience Letters, 2002 March 15, 321(5);1:100-104. 135: Chen C et al. Endogenous sex hormones and prostate cancer risk: a case-control study nested within the carotene and retinal efficacy trial. Cancer Epidimeiol Biomarkers Prev. 2003 Dec;12(12):1410-1416. 136: Upritchard J, Suterhland W, Mann J. Effect of supplementation with tomato juice, vitamin E, and vitamin C oxidation and products of inflammatory activity in type 2 diabetes. Diabetes Care. 2000 Jun;23(6):733-738. 137: Decker E, et al. Inhibition of low-density lipoprotein oxidation by carnosine histidine. J Agric Food Chem 2001 Jan;49(1):511-516. 138: Owen RW, et al. Olive oil consumption and health: the possible role of antioxidants. Lancet Oncol, 2000, Oct., 1:107-12. 139: Visioli F, et al. Antioxidant and other biological activities of phenols from olives and olive oil. Med Res Rev. 2002 Jan;22(1):65-75. 140: Simopoulos Ap. The traditional diet of Greece and cancer. Eur J Cancer Prev. 2004 Jun;13(3):219-30. 141: Visioli F., et al. Low density lipoprotein oxidation is inhibited in vitro by olive oil constituents. Atherosclerosis. 1995 Sep;117(1):25-32. 142: Cullinen K. Olive oil in the treatment of hypercholesterolemia. Med Health R.I. 2006 Mar;89(3):113. 143: Nagyova A, et al. Effects of dietary extra virgin olive oil on serum lipid resistance to oxidation and fatty acid composition in elderly lipidemic patients. The Cholesterol Conspiracy Podcast by Ladd McNamara, M.D. no 16:32 Episode 15: The “Best” Way to Reduce the Risk of Cardiac Death: Part 2 (According to Dr. Ladd McNamara) http://www.cholesterolconspiracy.com/episode-15-the-real-and-alternative-way-to-reduce-the-risk-of-death-from-heart-disease-and-stroke-part-2/ http://www.cholesterolconspiracy.com/episode-15-the-real-and-alternative-way-to-reduce-the-risk-of-death-from-heart-disease-and-stroke-part-2/#comments Tue, 24 Nov 2009 05:51:31 +0000 smp_admin http://www.cholesterolconspiracy.com/?p=74 In this episode Dr. Ladd McNamara discusses vitamins, minerals, antioxidants, and essential fatty acids: a real an alternative way to reduce the risk of death from heart disease and stroke.

  • Chapter 33: Vitamins, Minerals, Antioxidants, and Essential Fatty Acids: The Real Way to Reduce the Risk of Death from Heart Disease and Stroke – Part 2

Chapter Excerpts

Studies using levels of vitamin C, well above 700 mg per day have shown a decreased risk of diseases, including the risk of heart disease.

Ladd McNamara, M.D.

Bioflavanoids such as grape seed extract, resveratrol, & quercetin all have shown remarkable results in reducing the risk of heart disease and cancers. They work synergistically, as well as with other antioxidants to reduce the risk of disease.

L-carnosine may slow down the aging process, and protects the brain, skin, and arteries from damage. Furthermore, L-carnosine helps the heart to contract more effectively through enhancing the use of calcium.

Chapter References

  • 95: Mehra M, et al. Prevention of atherosclerosis. Postgraduate Med. 1995 98:1:175-182.
  • 96: Hoffman RM, et al. Antioxidants and the prevention of coronary heart disease. Arch Int Med. 1995 155:241-244.
  • 97: Morrison H, et al. Serum folate and risk of fatal coronary heart disease. J Am Med Assoc. 1996 275:24:1893-1896.
  • 98: Chasan-Taber L, et al. A prospective study of folate and vitamin B-6 and risk of myocardial infarction in U.S. physicians. J Am Coll Nutri. 1996 15:2:136-143.
  • 99: Levine GN, et al. Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation. 1996 93:6:1107-1113.
  • 100: Gatto LM, et al. Ascorbic acid induces a favorable lipoprotein profile in women. J Am Coll Nutri. 1996 15:2:154-158.
  • 101: Hallfrisch J, et al. High plasma vitamin c associated with high plasma HDL (1) – and HDL (2) cholesterol. Am J Clin Nutri. 1994 60:100-105.
  • 102: Osganian S, Stampfer M, Rimm E, Spiegelman D, et al. Vitamin C and risk of coronary heart disease in women. J Am Coll Cardiol. 2003 42:246-252.
  • 103: Rifici V, Khachadurian A. Dietary supplementation with vitamins C and E inhibits in-vitro oxidation of lipoproteins. J Am Coll Nutri. 1993 12:6:6331-6337.
  • 104: Gaziano J. Antioxidant vitamins and coronary artery disease risk. Am J Med. 1994 97:3A-18S-3A-21S.
  • 105: Lagrue G, et al. A study of the effects of procyanidol oligomers on capillary resistance in hypertension and in certain nephropathies. Sem Hop Paris. 1981 57:1399-1401.
  • 106: Detre A, et al. Studies on vascular permeability in hypertension: action of anthocyanosides. Clin Physiol Biochem. 1986 4:143-149.
  • 107: Meunier MT, et al. Free-radical scavenger activity of procyanidolic oligomers and anthocyanosides with respect to superoxide anion and lipid peroxidation. Plant Medphytother. 1989 4:267-274.
  • 108: Tixier J, et al. Evidence by in vivo and in vitro studies that binding of pycnogenols to elastin affects its rate of degradation by elastases. Biochem Parmacol. 1984 33:3933-3939.
  • 109: Facino R, et al. Free-radical scavenging action and anti-enzyme activities of procyanidines from vitis vinifera; a mechanism for their capillary protective action. Arzneimittel-Forschung Drug Research. 1994 44(1):5:592-601.
  • 110: Dartenuc JY, et al. Capillary resistance in the geriatric: study of a micro-angioprotector. Bordeaux Medicale. 1985 13:903.
  • 111: Kuhnau J. The flavonoids, a class of semi-essential food components: their role in human nutrition. World Rev Nutr Diet. 1976 24:117-191.
  • 112: Gabor M. Pharmacologic effects of flavonoids on blood vessels. Angiologica, 1972 9:355-374.
  • 113: Knekt P, et al. Flavonoid intake and coronary mortality in finland: a cohort study. Brit Med J. 1996 312:478-481.
  • 114: Stephens N, et al. Randomized Controlled Trial of Vitamin E in Patients with Coronary Disease: Cambridge Heart Anti-Oxidant Study (CHAOS). The Lancet. 1996 347:781-786.
  • 115: Niki E, et al. Interaction among vitamin C, vitamin E, and beta carotene. Am J Clin Nutri. 1995 62(suppl):1322S-1326S.
  • 116: Morrison H, et al. Serum folate and risk of fatal coronary heart disease. J Am Med Assoc. 1996 275:24:1893-1896.
  • 117: Carr A, Frei B. Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans. Am J Clin Nutr. 1999 69(6):1086-1107.
  • 118: Enstrom J. Counterpoint–vitamin C and mortality. Nutr Today. 1993 28:28-32.
  • 119: Osganian S, Stampfer M, Rimm E, et al. Vitamin C and risk of coronary heart disease in women. J Am Coll Cardiol. 2003 42(2):246-252.
  • 120: Keli S, et al. Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study. Arch Intern Med 1996 Mar 25;156?6):637-642.
  • 121: Duarte J, et al. Antihypertensive effects of the flavonoids quercetin in spontaneously hypertensive rats. Br J Pharmacol 2001 133:117-24.
  • 122: Maron D, Lu G, Cai N, et al. Cholesterol-lowering effect of a theaflavin-enriched green tea extract. A randomized controlled trial. Arch Intern Med. 2003;163:1448-1453.
  • 123: Preston JE, Hipkiss AR, Himsworth DT, et al. Toxic effects of betaamyloid (25-35) on immortalized rat brain endothelial cell: protection by carnosine, homocarnosine and beta-alamine. Neurosci Lett. 1998 242(2):1-0-108.
  • 124: Stadman ER. Protein oxidation and aging. Science. 1992 257(5074):1220-1224.
  • 125: Munch G, Schinzel R, Loske C, et al. Alzheimer’s disease – synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts. Journal of Neural Transmission. 1998 105(4-5):439-461.
  • 126: Bierhaus A, Hofmann MA, Ziegler R, et al. AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE Concept. Cardiovascular Research. 1998 37(3)586-600.
  • 127: McFarland GA, Holliday R. Retardation of the senescence of cultured human diploid fibroblasts by carnosine. Exp Cell Res. 1994 212(2):167-175.
  • 128: Zaloga GP, Roberts PR, Black KW. Carnosine is a novel peptide modulator of intracellular calcium and contractility in cardiac cells. Am J Physiol 1997 272(1 Pt 2):H462-468.
  • 129: Roberts PR, Zaloga GP. Cardiovascular effects of carnosine. Biochemistry (Mosc) 2000 Jul;65(7):856-861.

Ladd McNamara, M.D.

]]> http://www.cholesterolconspiracy.com/episode-15-the-real-and-alternative-way-to-reduce-the-risk-of-death-from-heart-disease-and-stroke-part-2/feed/ 0 Antioxidants,Bioflavanoids,Cholesterol Conspiracy,Essential Fatty Acids,Heart Disease,Ladd McNamara,Minerals,Stroke,Vitamins In this episode Dr. Ladd McNamara discusses vitamins, minerals, antioxidants, and essential fatty acids: a real an alternative way to reduce the risk of death from heart disease and stroke. - Chapter 33: Vitamins, Minerals, Antioxidants, In this episode Dr. Ladd McNamara discusses vitamins, minerals, antioxidants, and essential fatty acids: a real an alternative way to reduce the risk of death from heart disease and stroke. Chapter 33: Vitamins, Minerals, Antioxidants, and Essential Fatty Acids: The Real Way to Reduce the Risk of Death from Heart Disease and Stroke - Part 2 Chapter Excerpts Studies using levels of vitamin C, well above 700 mg per day have shown a decreased risk of diseases, including the risk of heart disease. Ladd McNamara, M.D. Bioflavanoids such as grape seed extract, resveratrol, & quercetin all have shown remarkable results in reducing the risk of heart disease and cancers. They work synergistically, as well as with other antioxidants to reduce the risk of disease. L-carnosine may slow down the aging process, and protects the brain, skin, and arteries from damage. Furthermore, L-carnosine helps the heart to contract more effectively through enhancing the use of calcium. Chapter References 95: Mehra M, et al. Prevention of atherosclerosis. Postgraduate Med. 1995 98:1:175-182. 96: Hoffman RM, et al. Antioxidants and the prevention of coronary heart disease. Arch Int Med. 1995 155:241-244. 97: Morrison H, et al. Serum folate and risk of fatal coronary heart disease. J Am Med Assoc. 1996 275:24:1893-1896. 98: Chasan-Taber L, et al. A prospective study of folate and vitamin B-6 and risk of myocardial infarction in U.S. physicians. J Am Coll Nutri. 1996 15:2:136-143. 99: Levine GN, et al. Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation. 1996 93:6:1107-1113. 100: Gatto LM, et al. Ascorbic acid induces a favorable lipoprotein profile in women. J Am Coll Nutri. 1996 15:2:154-158. 101: Hallfrisch J, et al. High plasma vitamin c associated with high plasma HDL (1) - and HDL (2) cholesterol. Am J Clin Nutri. 1994 60:100-105. 102: Osganian S, Stampfer M, Rimm E, Spiegelman D, et al. Vitamin C and risk of coronary heart disease in women. J Am Coll Cardiol. 2003 42:246-252. 103: Rifici V, Khachadurian A. Dietary supplementation with vitamins C and E inhibits in-vitro oxidation of lipoproteins. J Am Coll Nutri. 1993 12:6:6331-6337. 104: Gaziano J. Antioxidant vitamins and coronary artery disease risk. Am J Med. 1994 97:3A-18S-3A-21S. 105: Lagrue G, et al. A study of the effects of procyanidol oligomers on capillary resistance in hypertension and in certain nephropathies. Sem Hop Paris. 1981 57:1399-1401. 106: Detre A, et al. Studies on vascular permeability in hypertension: action of anthocyanosides. Clin Physiol Biochem. 1986 4:143-149. 107: Meunier MT, et al. Free-radical scavenger activity of procyanidolic oligomers and anthocyanosides with respect to superoxide anion and lipid peroxidation. Plant Medphytother. 1989 4:267-274. 108: Tixier J, et al. Evidence by in vivo and in vitro studies that binding of pycnogenols to elastin affects its rate of degradation by elastases. Biochem Parmacol. 1984 33:3933-3939. 109: Facino R, et al. Free-radical scavenging action and anti-enzyme activities of procyanidines from vitis vinifera; a mechanism for their capillary protective action. Arzneimittel-Forschung Drug Research. 1994 44(1):5:592-601. 110: Dartenuc JY, et al. Capillary resistance in the geriatric: study of a micro-angioprotector. Bordeaux Medicale. 1985 13:903. 111: Kuhnau J. The flavonoids, a class of semi-essential food components: their role in human nutrition. World Rev Nutr Diet. 1976 24:117-191. 112: Gabor M. Pharmacologic effects of flavonoids on blood vessels. Angiologica, 1972 9:355-374. 113: Knekt P, et al. Flavonoid intake and coronary mortality in finland: a cohort study. Brit Med J. 1996 312:478-481. 114: Stephens N, et al. Randomized Controlled Trial of Vitamin E in Patients with Coronary Disease: Cambridge Heart Anti-Oxidant Study (CHAOS). The Lancet. 1996 347:781-786. 115: Niki E, et al. The Cholesterol Conspiracy Podcast by Ladd McNamara, M.D. no 14:28 Episode 14: The “Best” Way to Reduce the Risk of Cardiac Death: Part 1 (According to Dr. Ladd McNamara) http://www.cholesterolconspiracy.com/episode-14-a-real-and-alternative-way-to-reduce-the-risk-of-death-from-heart-disease-and-stroke-part-1/ http://www.cholesterolconspiracy.com/episode-14-a-real-and-alternative-way-to-reduce-the-risk-of-death-from-heart-disease-and-stroke-part-1/#comments Wed, 18 Nov 2009 06:50:41 +0000 laddmcnamara http://www.cholesterolconspiracy.com/?p=69 In this episode Dr. Ladd McNamara discusses vitamins, minerals, antioxidants, and essential fatty acids: a real an alternative way to reduce the risk of death from heart disease and stroke.

  • Chapter 33: Vitamins, Minerals, Antioxidants, and Essential Fatty Acids: The Real Way to Reduce the Risk of Death from Heart Disease and Stroke – Part 1

Chapter Excerpts

The answer to lowering the risk of arteriosclerosis, heart disease and stroke is to reduce the oxidative damage to the LDL cholesterol, triglycerides, and the arterial lining so that plaque does not form.

The Cholesterol Conspiracy is about the makers of statin drugs hiding the truth that antioxidants work better than the statin drugs to reduce the risk of cardiac death. Antioxidants appear to be much more effective in reducing the risk of death from heart disease than current treatments using aspirin or cholesterol-lowering drugs combined.

There is a balance of D-alpha tocopherol and gamma tocopherol that is required to protect the fat and the protein components, respectively, or LDL cholesterol from oxidation. LDL that is not oxidized does not stick to the arterial walls.

Ladd McNamara, M.D.

Chapter References

  • 85: Aviram M. HDL–associated paraoxonase 1 (PON1) and dietaryantioxidants attenuate lipoprotein oxidation, macrophage foam cells formation and atherosclerosis development. Pathophysiol Haemost Thromb. 2006;35(1-2):146-51.
  • 86: Hertog M, Feskens E, Hollman P, Katan M, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly study. Lancet 1993 Oct 23;342(8878):1007-1011.
  • 87: Street D, et al. A population based case control study of the association of serum antioxidants and myocardial infarction. Am J Epidemiol. 1991 134:719-720.
  • 88: Steinberg D, et al. Antioxidants in the prevention of human atherosclerosis. Circulation. 1992 85:6:2338-2343.
  • 89: Gey K, et al. Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology. Am J Clin Nutri. 1991 53:326S-334S.
  • 90: Stampfer M, et al. Vitamin E consumption and the risk of coronary disease in women. New Engl J Med. 1993 328:1444-1449.
  • 91: Rimm E, Stampfer M, et al. Vitamin E consumption and the risk of coronary artery disease in men. New Engl J Med. 1993 328:1450-1456.
  • 92: Munteanu, A. et al. Anti-atherosclerotic effects of vitamin E – Myth or reality? J Cell Mol Med., 2004, Jan-Mar;8(1):59-76.
  • 93: I-Min Lee, et al. Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer. JAMA. 2005, Vol. 294, 56-65.
  • 94: Losonczy K, et al. Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the established populations for epidemiologic studies of the elderly. Am J Clin Nutri. 1996 64:190-196.

Ladd McNamara, M.D.

]]> http://www.cholesterolconspiracy.com/episode-14-a-real-and-alternative-way-to-reduce-the-risk-of-death-from-heart-disease-and-stroke-part-1/feed/ 0 Antioxidants,Cholesterol Conspiracy,Essential Fatty Acids,Ladd McNamara,Minerals,Vitamin C,Vitamin E,Vitamins In this episode Dr. Ladd McNamara discusses vitamins, minerals, antioxidants, and essential fatty acids: a real an alternative way to reduce the risk of death from heart disease and stroke. - Chapter 33: Vitamins, Minerals, Antioxidants, In this episode Dr. Ladd McNamara discusses vitamins, minerals, antioxidants, and essential fatty acids: a real an alternative way to reduce the risk of death from heart disease and stroke. Chapter 33: Vitamins, Minerals, Antioxidants, and Essential Fatty Acids: The Real Way to Reduce the Risk of Death from Heart Disease and Stroke - Part 1 Chapter Excerpts The answer to lowering the risk of arteriosclerosis, heart disease and stroke is to reduce the oxidative damage to the LDL cholesterol, triglycerides, and the arterial lining so that plaque does not form. The Cholesterol Conspiracy is about the makers of statin drugs hiding the truth that antioxidants work better than the statin drugs to reduce the risk of cardiac death. Antioxidants appear to be much more effective in reducing the risk of death from heart disease than current treatments using aspirin or cholesterol-lowering drugs combined. There is a balance of D-alpha tocopherol and gamma tocopherol that is required to protect the fat and the protein components, respectively, or LDL cholesterol from oxidation. LDL that is not oxidized does not stick to the arterial walls. Ladd McNamara, M.D. Chapter References 85: Aviram M. HDL--associated paraoxonase 1 (PON1) and dietaryantioxidants attenuate lipoprotein oxidation, macrophage foam cells formation and atherosclerosis development. Pathophysiol Haemost Thromb. 2006;35(1-2):146-51. 86: Hertog M, Feskens E, Hollman P, Katan M, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly study. Lancet 1993 Oct 23;342(8878):1007-1011. 87: Street D, et al. A population based case control study of the association of serum antioxidants and myocardial infarction. Am J Epidemiol. 1991 134:719-720. 88: Steinberg D, et al. Antioxidants in the prevention of human atherosclerosis. Circulation. 1992 85:6:2338-2343. 89: Gey K, et al. Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology. Am J Clin Nutri. 1991 53:326S-334S. 90: Stampfer M, et al. Vitamin E consumption and the risk of coronary disease in women. New Engl J Med. 1993 328:1444-1449. 91: Rimm E, Stampfer M, et al. Vitamin E consumption and the risk of coronary artery disease in men. New Engl J Med. 1993 328:1450-1456. 92: Munteanu, A. et al. Anti-atherosclerotic effects of vitamin E – Myth or reality? J Cell Mol Med., 2004, Jan-Mar;8(1):59-76. 93: I-Min Lee, et al. Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer. JAMA. 2005, Vol. 294, 56-65. 94: Losonczy K, et al. Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the established populations for epidemiologic studies of the elderly. Am J Clin Nutri. 1996 64:190-196. Ladd McNamara, M.D. The Cholesterol Conspiracy Podcast by Ladd McNamara, M.D. no 14:42 Episode 11: Vitamins and Statin Drugs http://www.cholesterolconspiracy.com/episode-11-vitamins-and-statin-drugs/ http://www.cholesterolconspiracy.com/episode-11-vitamins-and-statin-drugs/#comments Wed, 14 Oct 2009 05:00:57 +0000 laddmcnamara http://www.cholesterolconspiracy.com/?p=60 In this episode Dr. McNamara discusses vitamins verses statin drugs, and asks, "Which Makes More Sense?"

  • Chapter 28: Which Makes More Sense?
  • Chapter 29: Adding Vitamins to Statin Drugs

Chapter Excerpts

Medications, even taken the way they’re prescribed, are the third leading cause of death in the United States after cardiovascular disease and cancer. Over 100,000 people die every year in the United States from taking prescription medications.

The drug manufacturers will never admit that it is the antioxidants that reduce disease and death. In order to make money, the industry needs to sell you patented drugs, …not convince you that you should be taking vitamins and minerals.

Chapter References

  • 56: Rosenson RS. Statins in atherosclerosis: lipid-lowering agents with antioxidant capabilities. Atherosclerosis. 2004. Mar;173(1):1-12.
  • 57: Tsimikas S, et al. High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial. Circulation. 2004 Sep 14;110(11):1406-12.
  • 58: Sparks DL., et al. Statin therapy in Alzheimer’s disease. Acta Neurol Scand Suppl. 2006;185:78-86.
  • 59: Wolozin B., et al. Re-assessing the relationship between cholesterol, statins and Alzheimer’s disease. Acta Neurol Scand Suppl. 2006;185:63-70.
  • 60: Nunomura A, et al. Involvement of oxidative stress in Alzheimer disease. J Neuropathol Exp Neurol. 2006. Jul;65(7):631-41.
  • 61: Harman D. Alzheimer’s disease pathogenesis: role of aging. Ann NY Acad Sci. 2006 May;1067:454-60.
  • 62: Moreira PI, et al. Therapeutic options in Alzheimer’s disease. Expert Rev Neurother. 2006 Jun;6(6):897-910.
  • 63: Ono K., et al. Anti-amyloidogenic effects of antioxidants: implications for the prevention and therapeutics of Alzheimer’s disease. Biochim Biophys Acta. 2006 Jun;1762(6):575-86.
  • 64: Montiel T, et al. Role of oxidative stress on beta-amyloid neurotoxicity elicited during impairment of energy metabolism in the hippocampus: Protection by antioxidants. Exp Neurol. 2006 Apr 18; [Epub ahead of print].
  • 65: Ono K, Yamada M. Antioxidant compounds have potent antifibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro. J Neurochem. 2006 Apr;97(1):105-15. Epub 2006 Mar 8.
  • 66: Hajieva P, Behl C. Antioxidants as a potential therapy against age-related neurodegenerative diseases: amyloid Beta toxicity and Alzheimer’s disease. Curr Pharm Des. 2006;12(6):699-704.
  • 38: Langsjoen P, Langsjoen A. The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10. A review of animal and human publications. Biofactors. 2003 18(1-4):101-111.
  • 67: Passi S, Stancato A, Aleo E, Dmitrieva A, Littarru GP. Statins lower plasma and lymphocyte ugiquinol/ubiqinone without affecting other antioxidants and PUFA. Biofactors 2003 18(1-4):113-124.
  • 68: Mortensen S, Leth A, Agner E, Rohde M. Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors. Mol Aspects Med. 1997 18(suppl):S137-S144.
  • 69: Folkers K, Langsjoen P, Willis R, et al. Lovastatin decreases coenzyme Q10 levels in humans. Proc Natl Acad Sci USA. 1990 Nov; 87(22):8931-8934.
  • 70: Quiles J, Farquharson A, Ramirez-Tortosa M, et al. Coenzyme Q10 differentially moderates phospholipid hydroperoxide glutathionate peroxidase gene expression and free radicals production in malignant and non-malignant prostate cancer. Biofactors 2003 18(1-4):265-270.
]]> http://www.cholesterolconspiracy.com/episode-11-vitamins-and-statin-drugs/feed/ 0 Statin Drugs,Vitamins In this episode Dr. McNamara discusses vitamins verses statin drugs, and asks, "Which Makes More Sense?" Chapter 28: Which Makes More Sense? Chapter 29: Adding Vitamins to Statin Drugs Chapter Excerpts Medications, In this episode Dr. McNamara discusses vitamins verses statin drugs, and asks, "Which Makes More Sense?" Chapter 28: Which Makes More Sense? Chapter 29: Adding Vitamins to Statin Drugs Chapter Excerpts Medications, even taken the way they're prescribed, are the third leading cause of death in the United States after cardiovascular disease and cancer. Over 100,000 people die every year in the United States from taking prescription medications. The drug manufacturers will never admit that it is the antioxidants that reduce disease and death. In order to make money, the industry needs to sell you patented drugs, ...not convince you that you should be taking vitamins and minerals. Chapter References 56: Rosenson RS. Statins in atherosclerosis: lipid-lowering agents with antioxidant capabilities. Atherosclerosis. 2004. Mar;173(1):1-12. 57: Tsimikas S, et al. High-dose atorvastatin reduces total plasma levels of oxidized phospholipids and immune complexes present on apolipoprotein B-100 in patients with acute coronary syndromes in the MIRACL trial. Circulation. 2004 Sep 14;110(11):1406-12. 58: Sparks DL., et al. Statin therapy in Alzheimer’s disease. Acta Neurol Scand Suppl. 2006;185:78-86. 59: Wolozin B., et al. Re-assessing the relationship between cholesterol, statins and Alzheimer’s disease. Acta Neurol Scand Suppl. 2006;185:63-70. 60: Nunomura A, et al. Involvement of oxidative stress in Alzheimer disease. J Neuropathol Exp Neurol. 2006. Jul;65(7):631-41. 61: Harman D. Alzheimer’s disease pathogenesis: role of aging. Ann NY Acad Sci. 2006 May;1067:454-60. 62: Moreira PI, et al. Therapeutic options in Alzheimer’s disease. Expert Rev Neurother. 2006 Jun;6(6):897-910. 63: Ono K., et al. Anti-amyloidogenic effects of antioxidants: implications for the prevention and therapeutics of Alzheimer’s disease. Biochim Biophys Acta. 2006 Jun;1762(6):575-86. 64: Montiel T, et al. Role of oxidative stress on beta-amyloid neurotoxicity elicited during impairment of energy metabolism in the hippocampus: Protection by antioxidants. Exp Neurol. 2006 Apr 18; [Epub ahead of print]. 65: Ono K, Yamada M. Antioxidant compounds have potent antifibrillogenic and fibril-destabilizing effects for alpha-synuclein fibrils in vitro. J Neurochem. 2006 Apr;97(1):105-15. Epub 2006 Mar 8. 66: Hajieva P, Behl C. Antioxidants as a potential therapy against age-related neurodegenerative diseases: amyloid Beta toxicity and Alzheimer’s disease. Curr Pharm Des. 2006;12(6):699-704. 38: Langsjoen P, Langsjoen A. The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10. A review of animal and human publications. Biofactors. 2003 18(1-4):101-111. 67: Passi S, Stancato A, Aleo E, Dmitrieva A, Littarru GP. Statins lower plasma and lymphocyte ugiquinol/ubiqinone without affecting other antioxidants and PUFA. Biofactors 2003 18(1-4):113-124. 68: Mortensen S, Leth A, Agner E, Rohde M. Dose-related decrease of serum coenzyme Q10 during treatment with HMG-CoA reductase inhibitors. Mol Aspects Med. 1997 18(suppl):S137-S144. 69: Folkers K, Langsjoen P, Willis R, et al. Lovastatin decreases coenzyme Q10 levels in humans. Proc Natl Acad Sci USA. 1990 Nov; 87(22):8931-8934. 70: Quiles J, Farquharson A, Ramirez-Tortosa M, et al. Coenzyme Q10 differentially moderates phospholipid hydroperoxide glutathionate peroxidase gene expression and free radicals production in malignant and non-malignant prostate cancer. Biofactors 2003 18(1-4):265-270. The Cholesterol Conspiracy Podcast by Ladd McNamara, M.D. no 12:37